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Abstract

Makrofol-DE 1-1 CC Polycarbonate is a class of polymeric solid state nuclear track detector which has many applications in various radiation detection fields.

Structural property studies using X-ray diffraction were performed on the non-irradiated and irradiated Makrofol samples. The intensities of the characteristic absorption bands were found to decrease predominantly with increasing the proton fluence in the ranges 0-5x10¹¹ ions/cm² indicating that the degradation is the dominant mechanism.

Non isothermal studies were carried out using thermo-gravimetric analysis (TGA) and differential thermo-gravimetric (DTG) to obtain information concerning the thermal stability for Makrofol detector. The obtained TGA thermograms indicated that the Makrofol detector decomposes in one main weight loss stage.

Using the TGA curves, both the onset temperature of decomposition and the activation energy of thermal decomposition were calculated. The results indicated that the proton irradiation of Makrofol detector in the fluence range 0-5x10¹¹ ions/cm² causes an initial scission that reduces the thermal stability of the Makrofol samples. The proton irradiation in the fluence range 5x10¹¹-1x10¹⁵ ions/cm² led to a more compact structure of Makrofol polymer, which resulted in an improvement in its thermal stability with an increase in the activation energy of thermal decomposition.

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: Abstract

applications of complexes are very important in different sectors like the pharmaceutical industrial. So, this study aimed to preparation sodium salts of amino acids complexes by using K2PtCl6, Cu (NO3)2.3H2O, HgCl2 and ZnCl2 as a ligand reaction with the sodium salts of the following amino acids: glycine (glyH), L-alanine (alaH), L-phenylalanine (pheH). The following complexes were isolated: Na [Pt(gly)Cl4] .0.5C2H5OH, [Cu(ala)2].0.5C2H5OH, [Pt(ala)3Cl].C2H5OH.4H2O, [Pt(phe)2Cl2].0.5C2H5OH.1.5H2O, [Hg(phe)2].9H2O, [Zn(phe)2].C2H5OH. The isolated complexes have been characterized by their elemental analysis’s solubility, conductivity measurements, IR, electronic absorption and C13 NMR spectra.

Keywords: Metal complexes, Amino acids, Characterization.

الملخص:

تطبيقات المعقدات مهمة جد ا في مجاالت مختلفة مثل الصناعات الدوائية، عليه است هدفت هذه الدراسة تح ضير معقدات أمالح الصوديوم أمالح مع الليكاندات كتفاعالت K2PtCl6, Cu (NO3)2.3H2O, HgCl2 and ZnCl2 معقدات بواسطة الصوديوم لألحماض األميني ة التالية: الجاليسي ين (glyH(، L- أالنين (alaH(، L- فينيل أالنين )pheH). وت م الحصول على ست معقدات مختلفة: Na [Pt(gly)Cl4] .0.5C2H5OH, [Cu(ala)2].0.5C2H5OH, [Pt(ala)3Cl].C2H5OH.4H2O, [Pt(phe)2Cl2].0.5C2H5OH.1.5H2O, [Hg(phe)2].9H2O, [Zn(phe)2].C2H5OH تم تشخيص هذه المركبات عن طريق تحليل العناصر المكونة لها وايجاد نسبتها باإلضافة إلى استعمال الطرق الفيزيائ ية األتية: درجة االنصهار، الذائ ب ية، التوصيل الكهربائي لمحاليلها، واألطي اف تحت الحمراء والمرئية وفوق البنفسجية إلى الرنين المغناطيسي.

الكلمات المفتاحية: المعقدات، األحماض األمينية، التشخيص.

:Abstract

This project includes and in deification the complexes of amino acid L-serine (serH) L-cysteine (cysH) , and L-threonin (thrH₂) with some ions of trace elements such as K₂ptCl₆ ,

Cu(NO₃)₂.3H₂O , ZnCl₂ and HgCl₂ were studied by Infrared-spectra ‘NMR from this identification studies can give the structure formed for the complexes with were prepare with amino acids :

Na[pt(ser)Cl₄] .0.5C₂H₅OH   ,[Hg(ser)₂] .9H₂O , [Cu(ser)₂] , Na[pt(cys)₂Cl₃].0.5C₂H₅OH.3H₂O and

Keywords: metal complexes – Amino acids – Characterization .

الملخص:                                                                                                                                                              تم في هذا البحث تحضير وتشخيص بعض المعقدات من تفاعل بعض من ايونات العناصر هي : Z(II) , Cu(II) , Pt(IV) , Hg(II)    مع الأحماض الأمينية مثل السستايين و السيرين و الثرونين و التي شخصت بعدة طرق منها طيف الأشعة تحت الحمراء والمرئية وفوق البنفسجية بالأضافة الى استعمال الطرق الفيزيائية الأتية : درجة الأنصهار والذائيبية والتوصيل الكهربائي لمحاليلها .

الكلمات المفتاحية : الأحماض الأمينية – المعقدات – التشخيص

Nasal carriage of MRSA among hospital personnel is a big problem in hospital environment. Accordingly, the main objective of current study was to determine the prevalence of MRSA among Health Care Workers (HCWs) in Yafran hospital. 108 HCWs samples of nasal swabs were collected, and cultured on Mannitol Salt Agar. The isolates were identified as S. aureus based on morphology. Besides, confirmatory tests were performed, including coagulase and catalase test. Finally, cefoxitin disc resistance was used to identify the MRSA strain. Antibiotic susceptibility testing of MRSA was performed according to the guidelines of the Clinical and Laboratory Standards Institute .

The results showed that, out of the 108 HCWs, 37 (34%) carried MRSA. MRSA carriage rate was highest among Administration Department workers 30 % compared to other professions, followed by Emergency Department workers 21% , Obstetrics and Gynecology workers 19 %, Radiology, Laboratory and Internal Medicine Department workers was 8% ,5% and 5% respectively. Tetracycline showed the highest rate of resistance among MRSA isolates 27%, followed by Vancomycin 22%. While the Ciprofloxacin showed less resistance 11%. In conclusions, the high rate of nasal MRSA carriage among healthcare workers found in this study is alarming and highlights the need for adjusted infection control measures to prevent MRSA transmission from HCWs to the vulnerable patient .

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